Please take a look at poisoner application rates.

*** It may be said this is a small statistical sample *** but when I look at my fights, it seems like poisoners *** were sharply downgraded. *** Level 39 mind control poison against a level 36 half-elf. civilized <502hp 461m 267mv 14743tnl (-22.86%) 8 PM> d A Filthy Sewer Drain The stench here is almost unbearable, followed by the filthy trickling of urine and the wretched smell of death that wafts through these tunnels. This is obviously a sewer of some sort, leading probably to a less confined place outside of the city. A trickle of light comes from the sewage door above you and another floorboard can be seen resting beneath you. You also notice a few words scrawled on the wall beside you. [Exits: up down] (Hide) Sotis the half-elf is here. *** 1 apply knock-out sotis inhaled civilized <502hp 461m 266mv 14743tnl (-22.86%) 8 PM> You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. You feel Sotis slacken as the poison takes affect and she falls to the ground. civilized <502hp 461m 266mv 14743tnl (-22.86%) 8 PM> apply mind-control sotis inhaled You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. Sotis slips from your grasp. Sotis yells 'Help! Someone is trying to poison me!' civilized <502hp 470m 310mv 14743tnl (-22.86%) 9 PM> A quiet hiss escapes from the top of the vial as your concoction turns a bright silver. *** 2 apply mind-control sotis inhaled You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. Sotis slips from your grasp. Sotis yells 'Help! Someone is trying to poison me!' Sotis is using: a silver ring set with a single malachite a silver ring set with a single malachite (Glowing) (Humming) the Ankh of Loch Terradian a jade pendant a worn studded leather shirt a silver-horned helm a blood-red veil some worn studded leather leggings knee-high leather boots a pair of earth-toned gloves plate vambraces decorated with red enamel a skin from the snow leopard a belt of black dragonscales a plain leather wristband a richly grained fur trimmed bracer a blessed dagger named 'Heartseeker' *** 3 apply mind-control sotis inhaled You step out of the shadows. You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. Sotis slips from your grasp. Sotis yells 'Help! Someone is trying to poison me!' civilized <502hp 470m 310mv 14743tnl (-22.86%) 9 PM> *** 4 A quiet hiss escapes from the top of the vial as your concoction turns a bright silver. apply mind-control sotis inhaled You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. Sotis slips from your grasp. Sotis yells 'Help! Someone is trying to poison me!' civilized <502hp 479m 354mv 14743tnl (-22.86%) 10 PM> *** 5 apply mind-control sotis inhaled You attempt to hide. You quickly pour the vial of poison on a cloth and cover the mouth and nose of Sotis. Sotis slips from your grasp. Sotis yells 'Help! Someone is trying to poison me!'